Thutmosis was the son of Amenhotep II Akheprure and Tyo (Tiaa). The date and place of his birth have not been found.
He had three marriages/partners. His first wife was Nefertari. They were married, but the date and place have not been found. They had no known children.
His second wife was Iaret. They were married, but the date and place have not been found. They had no known children.
His third wife was Mutemwiya. They were married, but the date and place have not been found. Their five known children were Amenhotep III Nebmare (?-<1353BC), Amunipet (?-?), Tentamun (?-?), Amenemhat (?-?) and Tuthmosis (?-?).
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