Margareta was the daughter of unknown parents. The date and place of her birth have not been found.
Her husband was Johann II von der Leiter, who she married in 1497. The place has not been found. Their five known children were Anna (c1510-c1560), Hans Christoph (?-1544), Hans Bruno (?-1544), Maria (?->1577) and Veronika (?->1574).