Lyse was the daughter of Ludwig von Laer and Catharina von Plettenberg. The date and place of her birth have not been found.
Her husband was Kraft II von Hatzfeld. They were married, but the date and place have not been found. Their six known children were Johann I (?->1360), Hille (?-?), Kraft III (?-?), Gottfried (?-?), Hildegard (?-?) and Eckard IV (?-?).